Introducing TYLENOL® with Naproxen: Now FDA Approved
A first-of-its-kind OTC combination to expand what's possible in pain management.
A new dual-mechanism analgesic to deliver fast-acting pain relief lasting 12 hours.
One dose. Two mechanisms. None of the dosing guesswork.
TYLENOL® with Naproxen combines the fast action of acetaminophen with the long-lasting analgesia of naproxen — 650mg of acetaminophen with 220mg of naproxen sodium in one dose. It starts working in under 30 minutes and keeps pain controlled for 12 hours.
The strength to change OTC pain management. Backed by a pain relief brand you trust.
Rigorously evaluated through eight distinct clinical studies. Building on a 70-year legacy of care-driven innovation and decades of unmatched leadership in acetaminophen science, safety, and stewardship.

